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It’s happened. The first children genetically engineered with the powerful DNA-editing tool called CRISPR-Cas9 have been born to a woman in China. Their altered genes will be passed to their children, and their children’s children. Join CRISPR’s co-discoverer, microbiologist Jennifer Doudna, as we explore the perils and the promise of this powerful technology. It is not the first time human ingenuity has created something capable of doing us great good and great harm. Are we up to the challenge of guiding how CRISPR will shape the future?
PARTICIPANTS: Jennifer Doudna, Jamie Metzl, William Hurlbut
MODERATOR: Guy McKhann
MORE INFO ABOUT THE PROGRAM AND
PARTICIPANTS: https://www.worldsciencefestiv....al.com/programs/cris
TOPICS
0:00 - Introduction
1:55 - Jennifer Doudna introduction
2:25 - How do we learn to use CRISPR technology wisely?
3:29 - The basics of understanding CRISPR
6:04 - Genetic engineering explainer film
7:39 - How can CRISPR help the worldwide food chain?
9:57 - Genetic disease treatment
14:25 - Improving quality of life
15:55 - Designer babies
17:55 - The gene drive
19:25 - Confronting the ethical implications of CRISPR
23:55 - Jennifer’s childhood in Hawaii
28:25 - Patents
32:08 - Importance of accuracy
32:40 - Germ cells vs somatic cells
35:58 - He Jiankui controversy
40:05 - What makes CRISPR dangerous?
43:48 - How do we enforce regulation of CRISPR use?
53:50 - The aftermath of He Jiankui’s work
1:09:25 - How do we make CRISPR technology accessible globally?
1:14:00 - How do we balance natural biology and CRISPR?
1:18:44 - How will CRISPR impact our future as a species?
PROGRAM CREDITS
- Produced by Nils Kongshaug
- Associate Produced by Emmalina Glinskis
- Music provided by APM
- Additional images and footage provided by: Getty Images, Shutterstock, Videoblocks.
- Recorded at the Simons Foundation's Gerald D. Fishbaum Auditorium
The Kavli Prize recognizes scientists for their seminal advances in astrophysics, nanoscience, and neuroscience. The series, “The Big, the Small, and the Complex,” is sponsored by The Kavli Foundation.
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Probability is the examination of uncertain processes, but it's useful for far more than games of chance: http://www.gresham.ac.uk/lectu....res-and-events/proba
The modern theory of probability is considered to have begun in 1654 with an exchange of letters between Blaise Pascal and Pierre de Fermat, and has developed since then into the discipline which examines uncertain processes. For example, although on tossing a coin you have no idea whether you will obtain heads or tails we know that if you keep doing it then in the long run it is very likely that the proportion of heads will be close to a half. The lecture will discuss this and other examples of random processes e.g. random walks and Brownian motion.
The transcript and downloadable versions of the lecture are available from the Gresham College website: http://www.gresham.ac.uk/lectu....res-and-events/proba
Gresham College has been giving free public lectures since 1597. This tradition continues today with all of our five or so public lectures a week being made available for free download from our website. There are currently over 1,500 lectures free to access or download from the website.
Website: http://www.gresham.ac.uk
Twitter: http://twitter.com/GreshamCollege
Facebook: https://www.facebook.com/greshamcollege
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Where do we get our mathematical symbols from? Why is the set of integers called ℤ ? When was the equals sign first used? How about zero? Good notation tends to catch on quickly, whereas bad notation can obscure beautiful theory.
The lecture explores how the introduction of new notation has paved the way for new leaps in understanding, and considers some mathematical quirks of language, such as what the number 4 in English has in common with the number 11 in Russian.
A lecture by Sarah Hart
The transcript and downloadable versions of the lecture are available from the Gresham College website:
http://www.gresham.ac.uk/lectu....res-and-events/maths
Gresham College has been giving free public lectures since 1597. This tradition continues today with all of our five or so public lectures a week being made available for free download from our website. There are currently over 2,000 lectures free to access or download from the website.
Website: https://gresham.ac.uk
Twitter: https://twitter.com/greshamcollege
Facebook: https://facebook.com/greshamcollege
Instagram: https://instagram.com/greshamcollege
Presented by Ron Eglash; co-hosted by the University of Michigan School of Information and the Library of Michigan; project made possible in part by the University of Michigan School of Information. For an audio transcript of this video, please visit https://drive.google.com/open?....id=13y47iQrviZN-oFX7 .
An Invisible Threat: The Relationship Between Microwave Technology and Health | ENDEVR Documentary
We cannot see the waves, we cannot hear them, we cannot touch them, but they are all around us, invading the air, irradiating our body and the environment. An Invisible Threat looks at the relationship between microwave technology and health, investigating the conflicts of interest among industry representatives, politicians, scientists and consumers that leave us unprotected to the effects of radiation. Wireless networks irradiate microwaves indiscriminately across cities, villages and the countryside of all developed countries. This increasing exposure disturbs the biological processes that are essential for the healthy growth of human beings, animals and plants – it especially affects children and teenagers.
Our investigation delves into three groups: the telecommunications industry (mobile telephone companies, MMF); official organisations (WHO, IARC, ICNIRP) and official scientific reports (BioInitiative, Interphone, CEFALO).
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ENDEVR explains the world we live in through high-class documentaries, special investigations, explainers videos and animations. We cover topics related to business, economics, geopolitics, social issues and everything in between that we think are interesting.