Probability is the backbone of science, but how well do you understand it? Odds are, not as well as you think; it is a surprisingly subtle concept that is often misunderstood, sometimes even by professionals who use it to guide crucial and far-reaching decisions. In this program, experts from technology, physics, medicine, and programming explore the slippery side of probability and the powerful role it plays in modern life.

This program is part of the Big Ideas Series, made possible with support from the John Templeton Foundation.

Original Program Date: May 30, 2015
Host: John Hockenberry
Participants: Robert Green, Leonard Mlodinow, Masoud Mohseni, Alan Peters

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Thomas Bayes and the history of A.I. 00:05

John Hockenberry's Introduction 5:48

Participant Introductions 8:51

What is the quantum notion of probability? 10:42

Googles dilation refrigerator 18:41

The Monty Hall problem 22:55

The Girl Named Florida problem 31:33

How does probability influence the medical field 40:45

How can people empower themselves with probability 54:08

How machines calculate probability 1:02:16

What is the Robo-naut? 1:12:50

Are humans relying on probability to determine lifestyle? 1:17:40

It’s happened. The first children genetically engineered with the powerful DNA-editing tool called CRISPR-Cas9 have been born to a woman in China. Their altered genes will be passed to their children, and their children’s children. Join CRISPR’s co-discoverer, microbiologist Jennifer Doudna, as we explore the perils and the promise of this powerful technology. It is not the first time human ingenuity has created something capable of doing us great good and great harm. Are we up to the challenge of guiding how CRISPR will shape the future?

PARTICIPANTS: Jennifer Doudna, Jamie Metzl, William Hurlbut

MODERATOR: Guy McKhann

MORE INFO ABOUT THE PROGRAM AND
PARTICIPANTS: https://www.worldsciencefestiv....al.com/programs/cris

TOPICS
0:00 - Introduction
1:55 - Jennifer Doudna introduction
2:25 - How do we learn to use CRISPR technology wisely?
3:29 - The basics of understanding CRISPR
6:04 - Genetic engineering explainer film
7:39 - How can CRISPR help the worldwide food chain?
9:57 - Genetic disease treatment
14:25 - Improving quality of life
15:55 - Designer babies
17:55 - The gene drive
19:25 - Confronting the ethical implications of CRISPR
23:55 - Jennifer’s childhood in Hawaii
28:25 - Patents
32:08 - Importance of accuracy
32:40 - Germ cells vs somatic cells
35:58 - He Jiankui controversy
40:05 - What makes CRISPR dangerous?
43:48 - How do we enforce regulation of CRISPR use?
53:50 - The aftermath of He Jiankui’s work
1:09:25 - How do we make CRISPR technology accessible globally?
1:14:00 - How do we balance natural biology and CRISPR?
1:18:44 - How will CRISPR impact our future as a species?

PROGRAM CREDITS
- Produced by Nils Kongshaug
- Associate Produced by Emmalina Glinskis
- Music provided by APM
- Additional images and footage provided by: Getty Images, Shutterstock, Videoblocks.
- Recorded at the Simons Foundation's Gerald D. Fishbaum Auditorium

The Kavli Prize recognizes scientists for their seminal advances in astrophysics, nanoscience, and neuroscience. The series, “The Big, the Small, and the Complex,” is sponsored by The Kavli Foundation.

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The lake is endowed with humble resources of fish on the eastern side that has always been a source of livelihoods for communities living along this lake.
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Where do we get our mathematical symbols from? Why is the set of integers called ℤ ? When was the equals sign first used? How about zero? Good notation tends to catch on quickly, whereas bad notation can obscure beautiful theory.

The lecture explores how the introduction of new notation has paved the way for new leaps in understanding, and considers some mathematical quirks of language, such as what the number 4 in English has in common with the number 11 in Russian.

A lecture by Sarah Hart

The transcript and downloadable versions of the lecture are available from the Gresham College website:
http://www.gresham.ac.uk/lectu....res-and-events/maths

Gresham College has been giving free public lectures since 1597. This tradition continues today with all of our five or so public lectures a week being made available for free download from our website. There are currently over 2,000 lectures free to access or download from the website.

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“My chances are 50-50. Not great odds. And that’s only to get to the starting line. The human race is not for the faint hearted, when half the runners are doomed to die, before the race gets started.”

This documentary film explores the development of the growing fetus from conception to delivery. Open a window into the hidden world of the foetus and explore each trimester in amazing detail. It’s meant to be a joyous event, but in reality, it's a gripping battle for survival. Using cutting edge technology, we go inside the womb and follow the incredible nine month journey from conception to birth, showing how the struggle for life turns into the miracle of birth. Enhanced by poet Roger McGough’s reading of a series of poems written for the occasion.

“Until now, I thought I was the universe. But everything that is, was within me. Now that I can touch these walls, I realise I must be deep inside a greater universe.”

Lucie Green takes us on a journey from the centre of the sun to planet earth in a run-down of the latest solar physics research.
Watch the Q&A here: https://www.youtube.com/watch?v=0JkxTILe2Nk

Lucie's book "15 Million Degrees: A Journey to the Centre of the Sun" is available to buy now - https://geni.us/2oB8V

110 times wider than Earth; 15 million degrees at its core; an atmosphere so huge that Earth is actually within it: come and meet the star of our solar system.

Light takes eight minutes to reach Earth from the surface of the Sun. But its journey within the Sun takes hundreds of thousands of years. What is going on in there? What are light and heat? How does the Sun produce them and how on earth did scientists discover this? Since the Royal Institution was founded in 1799 our knowledge of the Sun has changed dramatically and much of the work was carried out at the Ri.

Join Lucie Green for an enlightening talk, taking you from inside the Sun to its surface and to Earth, to discover how the Sun works, how a solar storm can threaten the modern technology that society relies on and more of the latest research in solar physics.

Lucie Green is a Professor of Physics based at the Mullard Space Science Laboratory, UCL’s Department of Space and Climate Physics. She studies activity in the atmosphere of our nearest star, the Sun. In particular, she looks at immense magnetic fields in the Sun’s atmosphere which sporadically erupt into the Solar System.

Lucie is very active in public engagement with science, regularly giving public talks and appearing on TV shows like Sky at Night.

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Join me Thursday October 29th at 2:30PM Eastern time as I welcome to the Mbongi, Psychologist and Africologist, Wade Nobles, PhD. Dr. Nobles is a founding member of the Association of Black Psychologists and former national President (1994-95). He is Professor Emeritus of Africana Studies and Black Psychology at San Francisco State University and the author of over one hundred (100) articles, chapters, research reports and books; the co-author of the seminal article in Black Psychology, Voodoo or IQ: An Introduction to African Psychology. In this conversation we will discuss Black Psychology today, in what areas it has been most successful and other areas needed currently to further permeate, and current and future works in the making. This will be a powerful powerful show that you do not want to miss. So set your reminder, like, and share with friends and colleagues.

In the meantime, GET YOUR COPY TODAY!
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Yvan Sagnet from Cameroon is battling modern slavery in Italy's agricultural sector. Sagnet once worked as a low-wage farmhand. Now he is fighting for the rights of seasonal farmworkers, taking criminal recruiters, or gangmasters, to court.

Yvan Sagnet calls them slaves: the hundreds of thousands of seasonal farmworkers from Africa and eastern Europe on Italy's fields. Without their labor the country would have no tomato, orange or olive harvest. But the workers are exploited and often forced to live under inhumane conditions in ruins or shanty towns called ghettos. In 2011 Sagnet himself briefly picked tomatoes on the fields near the southern Italian town of Nardò. For four days he labored to fill the 350-kilogram crates. He earned 14 euros a day, ten of which he had to hand over to the gangmaster, or Caporale, for transport and water. Caporale is the term for the criminal recruiters who control and exploit the workers. After a 14-hour day working under the blazing sun and even being beaten, Sagnet took home only four euros. He helped to organize the first strike among the farmhands. It was a success, and since then he has been an activist for the rights of the farmworkers and against the gangmasters. Despite death threats, he has set up an organization called NoCap, a label to certify produce farmed under ethically acceptable conditions. And he has taken his fight against exploitation and slavery to the courts. So far, the Italian justice system has responded slowly. It's a fight that will take a long time to win.

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