It’s happened. The first children genetically engineered with the powerful DNA-editing tool called CRISPR-Cas9 have been born to a woman in China. Their altered genes will be passed to their children, and their children’s children. Join CRISPR’s co-discoverer, microbiologist Jennifer Doudna, as we explore the perils and the promise of this powerful technology. It is not the first time human ingenuity has created something capable of doing us great good and great harm. Are we up to the challenge of guiding how CRISPR will shape the future?

PARTICIPANTS: Jennifer Doudna, Jamie Metzl, William Hurlbut

MODERATOR: Guy McKhann

MORE INFO ABOUT THE PROGRAM AND
PARTICIPANTS: https://www.worldsciencefestiv....al.com/programs/cris

TOPICS
0:00 - Introduction
1:55 - Jennifer Doudna introduction
2:25 - How do we learn to use CRISPR technology wisely?
3:29 - The basics of understanding CRISPR
6:04 - Genetic engineering explainer film
7:39 - How can CRISPR help the worldwide food chain?
9:57 - Genetic disease treatment
14:25 - Improving quality of life
15:55 - Designer babies
17:55 - The gene drive
19:25 - Confronting the ethical implications of CRISPR
23:55 - Jennifer’s childhood in Hawaii
28:25 - Patents
32:08 - Importance of accuracy
32:40 - Germ cells vs somatic cells
35:58 - He Jiankui controversy
40:05 - What makes CRISPR dangerous?
43:48 - How do we enforce regulation of CRISPR use?
53:50 - The aftermath of He Jiankui’s work
1:09:25 - How do we make CRISPR technology accessible globally?
1:14:00 - How do we balance natural biology and CRISPR?
1:18:44 - How will CRISPR impact our future as a species?

PROGRAM CREDITS
- Produced by Nils Kongshaug
- Associate Produced by Emmalina Glinskis
- Music provided by APM
- Additional images and footage provided by: Getty Images, Shutterstock, Videoblocks.
- Recorded at the Simons Foundation's Gerald D. Fishbaum Auditorium

The Kavli Prize recognizes scientists for their seminal advances in astrophysics, nanoscience, and neuroscience. The series, “The Big, the Small, and the Complex,” is sponsored by The Kavli Foundation.

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Black holes may hold the key to understanding the most fundamental truths of the universe, but how do you see something that’s, well, black? Astronomers think they have the answer. Thanks to a global array of radio telescopes that turn the Earth into a giant receiver, we may soon have the first picture of the event horizon of Sagittarius A*, the black hole at the center of the Milky Way galaxy. And, with the power of math, scientists are going even further, using equations to “look” inside black holes, peering at the central singularity where general relativity and quantum mechanics collide. Join Brian Greene and other leading physicists and astronomers on a journey to make darkness visible.

Find out more about the program and the participants: https://www.worldsciencefestiv....al.com/programs/dark

MODERATOR: Brian Greene
PARTICIPANTS: Shep Doeleman, Andrea Ghez, Vicky Kalogera, Cumrun Vafa

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The Big Ideas Series is supported in part by the John Templeton Foundation.

Filmed live at the 2018 World Science Festival

Where do we get our mathematical symbols from? Why is the set of integers called ℤ ? When was the equals sign first used? How about zero? Good notation tends to catch on quickly, whereas bad notation can obscure beautiful theory.

The lecture explores how the introduction of new notation has paved the way for new leaps in understanding, and considers some mathematical quirks of language, such as what the number 4 in English has in common with the number 11 in Russian.

A lecture by Sarah Hart

The transcript and downloadable versions of the lecture are available from the Gresham College website:
http://www.gresham.ac.uk/lectu....res-and-events/maths

Gresham College has been giving free public lectures since 1597. This tradition continues today with all of our five or so public lectures a week being made available for free download from our website. There are currently over 2,000 lectures free to access or download from the website.

Website: https://gresham.ac.uk
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Presented by Ron Eglash; co-hosted by the University of Michigan School of Information and the Library of Michigan; project made possible in part by the University of Michigan School of Information. For an audio transcript of this video, please visit https://drive.google.com/open?....id=13y47iQrviZN-oFX7 .

Thirty-five years ago string theory took physics by storm, promising the coveted unified theory of nature’s forces that Einstein valiantly sought but never found. In the intervening decades, string theory has brought a collection of mind-boggling possibilities into the lexicon of mainstream thinking—extra dimensions of space, holographic worlds, and multiple universes. Some researchers view these developments as symptoms of string theory having lost its way. Others argue that string theory, although very much still a work in progress, is revealing stunning new qualities of reality. Join leading minds in theoretical physics for a whirlwind ride through the twists and turns of string theory—its past, its future, and what it tells us about the search for the universe’s final theory.

PARTICIPANTS: Marcelo Gleiser, Michael Dine, Andrew Strominger

MODERATOR: Brian Greene

MORE INFO ABOUT THE PROGRAM AND
PARTICIPANTS: https://www.worldsciencefestiv....al.com/programs/loos

This program is part of the BIG IDEAS SERIES, made possible with support from the JOHN TEMPLETON FOUNDATION.

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TOPICS
0:00 - Introduction
3:54 - Program introduction
5:40 - Marcelo Gleiser introduction
6:26 - Unification of electricity and magnetism
10:30 - Unification of space and time
13:49 - Einstein’s General Theory of Relativity
18:38 - Standard model of particle physics
21:56 - Supersymmetry
26:14 - The Island of Knowledge
32:01 - Godel’s Incompleteness Theorems
34:27 - String Theory explainer film
37:07 - Michael Dine introduction
38:35 - Supersymmetry and the spectrum of particles
42:18 - Large Hadron Collider
44:57 - Extra dimensions of space
50:34 - Dark energy and multiple universes
56:40 - Progress since the 1980s and the future of particle physics
59:55 - Andrew Strominger introduction
1:00:53 - Einstein and black holes
1:03:59 - The black hole information paradox
1:07:30 - Stephen Hawking’s insights into black holes
1:12:00 - Using string theory to understand black holes
1:19:33 - Conformal symmetry
1:22:48 - Andrew Strominger’s view of string theory

CREDITS
- Produced by Laura Dattaro
- Associate Produced by Peter Goldberg
- Editing and Animation by Josh Zimmerman
- Music provided by APM
- Additional images and footage provided by: Getty Images, Shutterstock, Videoblocks, Event Horizon Telescope
- Recorded at NYU Skirball Center

This algebra and precalculus video tutorial explains how to solve exponential growth and decay word problems. It provides the formulas and equations / functions that you need to solve it. This video contains plenty of examples and practice problems.

My Website: https://www.video-tutor.net
Patreon Donations: https://www.patreon.com/MathScienceTutor
Amazon Store: https://www.amazon.com/shop/th....eorganicchemistrytut

Here is a list of example problems.
1. Population Growth of Rabbits on an island
2. Depreciation of car value
3. Appreciation of Home value
4. Exponential Growth Bacteria Problem - Finding how much will there if the bacteria doubles or triples every 20 minutes

Lucie Green takes us on a journey from the centre of the sun to planet earth in a run-down of the latest solar physics research.
Watch the Q&A here: https://www.youtube.com/watch?v=0JkxTILe2Nk

Lucie's book "15 Million Degrees: A Journey to the Centre of the Sun" is available to buy now - https://geni.us/2oB8V

110 times wider than Earth; 15 million degrees at its core; an atmosphere so huge that Earth is actually within it: come and meet the star of our solar system.

Light takes eight minutes to reach Earth from the surface of the Sun. But its journey within the Sun takes hundreds of thousands of years. What is going on in there? What are light and heat? How does the Sun produce them and how on earth did scientists discover this? Since the Royal Institution was founded in 1799 our knowledge of the Sun has changed dramatically and much of the work was carried out at the Ri.

Join Lucie Green for an enlightening talk, taking you from inside the Sun to its surface and to Earth, to discover how the Sun works, how a solar storm can threaten the modern technology that society relies on and more of the latest research in solar physics.

Lucie Green is a Professor of Physics based at the Mullard Space Science Laboratory, UCL’s Department of Space and Climate Physics. She studies activity in the atmosphere of our nearest star, the Sun. In particular, she looks at immense magnetic fields in the Sun’s atmosphere which sporadically erupt into the Solar System.

Lucie is very active in public engagement with science, regularly giving public talks and appearing on TV shows like Sky at Night.

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