It’s happened. The first children genetically engineered with the powerful DNA-editing tool called CRISPR-Cas9 have been born to a woman in China. Their altered genes will be passed to their children, and their children’s children. Join CRISPR’s co-discoverer, microbiologist Jennifer Doudna, as we explore the perils and the promise of this powerful technology. It is not the first time human ingenuity has created something capable of doing us great good and great harm. Are we up to the challenge of guiding how CRISPR will shape the future?

PARTICIPANTS: Jennifer Doudna, Jamie Metzl, William Hurlbut

MODERATOR: Guy McKhann

MORE INFO ABOUT THE PROGRAM AND
PARTICIPANTS: https://www.worldsciencefestiv....al.com/programs/cris

TOPICS
0:00 - Introduction
1:55 - Jennifer Doudna introduction
2:25 - How do we learn to use CRISPR technology wisely?
3:29 - The basics of understanding CRISPR
6:04 - Genetic engineering explainer film
7:39 - How can CRISPR help the worldwide food chain?
9:57 - Genetic disease treatment
14:25 - Improving quality of life
15:55 - Designer babies
17:55 - The gene drive
19:25 - Confronting the ethical implications of CRISPR
23:55 - Jennifer’s childhood in Hawaii
28:25 - Patents
32:08 - Importance of accuracy
32:40 - Germ cells vs somatic cells
35:58 - He Jiankui controversy
40:05 - What makes CRISPR dangerous?
43:48 - How do we enforce regulation of CRISPR use?
53:50 - The aftermath of He Jiankui’s work
1:09:25 - How do we make CRISPR technology accessible globally?
1:14:00 - How do we balance natural biology and CRISPR?
1:18:44 - How will CRISPR impact our future as a species?

PROGRAM CREDITS
- Produced by Nils Kongshaug
- Associate Produced by Emmalina Glinskis
- Music provided by APM
- Additional images and footage provided by: Getty Images, Shutterstock, Videoblocks.
- Recorded at the Simons Foundation's Gerald D. Fishbaum Auditorium

The Kavli Prize recognizes scientists for their seminal advances in astrophysics, nanoscience, and neuroscience. The series, “The Big, the Small, and the Complex,” is sponsored by The Kavli Foundation.

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Black holes may hold the key to understanding the most fundamental truths of the universe, but how do you see something that’s, well, black? Astronomers think they have the answer. Thanks to a global array of radio telescopes that turn the Earth into a giant receiver, we may soon have the first picture of the event horizon of Sagittarius A*, the black hole at the center of the Milky Way galaxy. And, with the power of math, scientists are going even further, using equations to “look” inside black holes, peering at the central singularity where general relativity and quantum mechanics collide. Join Brian Greene and other leading physicists and astronomers on a journey to make darkness visible.

Find out more about the program and the participants: https://www.worldsciencefestiv....al.com/programs/dark

MODERATOR: Brian Greene
PARTICIPANTS: Shep Doeleman, Andrea Ghez, Vicky Kalogera, Cumrun Vafa

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The Big Ideas Series is supported in part by the John Templeton Foundation.

Filmed live at the 2018 World Science Festival

Easy to understand animation explaining all basic concepts.

This algebra and precalculus video tutorial explains how to solve exponential growth and decay word problems. It provides the formulas and equations / functions that you need to solve it. This video contains plenty of examples and practice problems.

My Website: https://www.video-tutor.net
Patreon Donations: https://www.patreon.com/MathScienceTutor
Amazon Store: https://www.amazon.com/shop/th....eorganicchemistrytut

Here is a list of example problems.
1. Population Growth of Rabbits on an island
2. Depreciation of car value
3. Appreciation of Home value
4. Exponential Growth Bacteria Problem - Finding how much will there if the bacteria doubles or triples every 20 minutes

Exponential Growth

Paul Andersen explains how populations eventually reach a carrying capacity in logistic growth. He begins with a brief discussion of population size ( N ), growth rate ( r ) and exponential growth. He then explains how density dependent limiting factors eventually decrease the growth rate until a population reaches a carrying capacity ( K ). A mathematical simulation of this process is included along with a brief discussion of r and K selected species.

Intro Music Atribution
Title: I4dsong_loop_main.wav
Artist: CosmicD
Link to sound: http://www.freesound.org/peopl....e/CosmicD/sounds/725
Creative Commons Atribution License

All images are either Public Domain or Creative Commons Attribution Licenses:
"File:Frog in Frogspawn.jpg." Wikipedia, the Free Encyclopedia. Accessed April 19, 2013. http://en.wikipedia.org/wiki/F....ile:Frog_in_frogspaw
"File:Stress-coloured Brookesia Desperata Female with Two Recently Laid Eggs.png." Wikipedia, the Free Encyclopedia. Accessed April 19, 2013. http://en.wikipedia.org/wiki/F....ile:Stress-coloured_
Nevit. English: White Rabbit, 2011. Own work. https://commons.wikimedia.org/....wiki/File:Rabbit_nev

General Toussaint L'ouverture: What You Didn't Know About the Haitian Revolution with King Kevin Dorival http://www.kevindorival com

$Courage2believe - Gift for Professor Jean-Claude Exulien Donations can be mailed: PO Box 150071 Atlanta, GA. 30315#HaitianFlagDay #ToussaintLouverture #haitianrevolution

A quick overview of some African descended authors from various Black communities throughout the country.

Sign up for a free Audible trial at https://audible.com/greatwar or text greatwar to 500-500

Following the Spanish-American War, the United States foreign policy, under the influence of the Monroe Doctrine, intervened in several countries in Central America and the Caribbean. The United States Marine Corps was usually the military arm of these involvements as was the case in Cuba, Haiti and the Dominican Republic.

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» SOURCES
Bauduy, Jennifer, “The 1915 U.S. Invasion of Haiti: Examining a Treaty of Occupation” Social Education 79 (2015)

Castor, Suzy & Garafola, Lynn, “The American Occupation of Haiti (1915-34) and the Dominican Republic (1916-24)” The Massachusetts Review, Vol. 15, No. 1/2, Caliban (Winter - Spring, 1974)

Gilderhus, Mark T, The Second Century: U.S.-Latin American Relations Since 1889, (Wilmington, Delaware : Scholarly Resources Inc, 2000)

Johnson, Jeannie L. The Marines, Counterinsurgency, and Strategic Culture: Lessons Learned and Lost in America's Wars, (Washington D.C. : Georgetown University Press, 2018)

Langley, Lester D, The Banana Wars: United States Intervention in the Caribbean, 1898-1934, (Wilmington, Delaware : Scholarly Resources Inc, 2002)

Langley, Lester D, The United States and the Caribbean, 1900-1970, (Athens, Georgia : University of Georgia Press, 1980)

Perez, Louis A., Jr. Intervention, Revolution, and Politics in Cuba, 1913-1921, (Pittsburgh, Pennsylvania : University of Pittsburgh Press, 2009)

Posner, Walter H. “American Marines in Haiti, 1915-1922” The Americas, Vol. 20, No. 3 (Jan., 1964)

Schreadley, R. L. Intervention! : the Americans in Haiti, 1915-1934, (Charleston, South Carolina : Evening Post Books, 2017)

Yates, Lawrence A, “The US Military’s Experience in Stability Operations, 1789-2005”, Global War on Terrorism Occasional Paper 15, Title 1, Series 2, (2006)


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»CREDITS
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Written by: Mark Newton, Jesse Alexander
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Director of Photography: Toni Steller
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